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Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS

Sci Adv 9(42):eabp9530 Chen Y et al (2020) LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy

The complexity of their pathophysiological mechanisms, coupled with the limitations of current targeted therapies, complicates the development of effective treatments

[Google Scholar] 16.Kirsch I., Sapirstein G

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Similarly, real-world practice often involves individualized and multimodal care, whereas RCTs generally isolate single interventions