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He said the data suggested that very heavy marijuana use was linked to adverse effects on pulmonary function similar to tobacco use.

However, tobacco use rates among those with substance use disorders remain very high

Cardiovascular Effects Nicotine itself can: Raise heart rate Increase blood pressure Constrict blood vessels For people with heart disease or cardiovascular risk factors, nicotine remains a concern regardless of delivery method

In fact, cannabis withdrawal syndrome is now listed in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) as a real condition

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Vivid dreams and nausea are not uncommon, as with cytisine, but later studies showed the drug to be safe for patients who are in a mentally sound place