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Instillation of Anti-Neoplastic Pharmacologic/Biologic Agent Into Renal Pelvis (APC 1551) Effective October 1, 2023, CMS established HCPCS code C9789 (Instillation of anti-neoplastic pharmacologic/biologic agent into renal pelvis, any method, including all imaging guidance, including volumetric measurement if performed) and assigned it to APC 1559 (New TechnologyLevel 22 ($2001-$2500)), with a payment rate of $2,250.50 based on our review of the clinical and resource characteristics of this service

Dall'Oglio F, Puviani M, Milani M, Micali G

Published veterinary research on the peptide contributed to understanding of its mechanisms and safety profile, though this animal data has not been directly replicated in human clinical trials

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Primary peptide: KPV at 200 to 400 mcg subcutaneously daily Support peptide: Thymosin alpha-1 at 1.6 mg subcutaneously twice weekly Implementation schedule: Pre-season (4 weeks before): Begin KPV daily and Ta1 twice weekly to stabilize mast cells and rebalance Th1/Th2 ratio before allergen exposure peaks During season: Continue both peptides at the same doses throughout the allergy season Post-season: Taper KPV over 2 weeks