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58 The decrease in autophagy in aged HSCs leads to the accumulation of active and healthy mitochondria and increased metabolism, particularly increased oxidative phosphorylation, promoting accelerated myeloid differentiation of HSCs

The patients were tested positive for increased ESR level and rheumatoid factor

For example, MET gene mutation and amplification represent one of the major mechanisms causing constitutive active HGF/c-MET signaling in cancer cells

Sekirov I, Russell SL, Antunes CM, et al