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The potential mechanism is shown as following (Figure 1)

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Key emerging trends include the growing popularity of Lions Mane mushroom, the expanding use of creatine monohydrate for cognitive support (beyond its traditional role in muscle health), and increased interest in well-researched probiotics such as Lactobacillus rhamnosus GG and multi-species probiotic blends

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The overexpression of EGFR reduces intracellular ROS levels through the PI3K/AKT pathway, thereby enhancing the metastatic potential of cancer cells [100] (Fig