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Specifically, the loss of glutaryl-CoA dehydrogenase leads to intracellular accumulation of glutaryl-CoA, promoting NRF2 glutarylation

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[DOI] [PubMed] [Google Scholar] 6.Liao R., Nascimben L., Friedrich J., Gwathmey J.K., Ingwall J.S

PMID: 35934392 Front Microbiol Enrofloxacin Promotes Plasmid-Mediated Conjugation Transfer of Fluoroquinolone-Resistance Gene qnrS

Stress-dependent alterations of E GSH caused by a transient draw of electrons from the glutathione redox buffer for oxidant detoxification and coupling of E GSH to target proteins thus may result in altered protein function and hence pronounced metabolic and developmental consequences for individual cells and the whole organism