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Its unique -glutamyl linkage rather than the standard -peptide bond between Glu and Cys confers resistance to most peptidases and extends its intracellular half-life substantially

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3.1 Changes in sleep with aging Sleep serves a restorative role, allowing the brain and body to recover from the oxidative and metabolic demands of wakefulness

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They are typically administered via subcutaneous injection, though some may be available in oral, nasal, or topical forms