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Notably, RNA-metabolite correlations exhibited a broader dispersion in extreme ranges than their protein-metabolite counterparts, implying a greater transcriptional regulatory amplitude

Kaarteenaho-Wiik R

ISBN 978-3-0348-0664-0

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doi: 10.3390/antiox9100914 110 HadzicT.LiL.ChengN.WalshS

These models allow researchers to zero in on and study the target TSH receptor, thyroid follicular cells, and the feedback mechanisms along the HPT axis to gain insight into how dysregulated thyroid hormone signaling contributes to metabolic disturbances associated with hyperthyroidism Kohn et al