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In addition to the SRE, later it was shown that SREBP-1c can bind to E-boxes (CAXXTG) (48)

doi: 10.1042/BSR20220200 9 MengXMNikolic-PatersonDJLanHY

On the other hand, treatment with lithium chloride, an autophagy inducer, had negative results in a preclinical mouse model [88] and in patients [175], which may raise questions on the likelihood of autophagy as a promising target

Supplementary material The Supplementary Material for this article can be found online at: Abbreviations ACTH, Adrenocorticotropic hormone

The pathology of -syn aggregation and dopaminergic neuron loss in the peripheral skin resembles that in the central nervous system, indicating a strong correlation between cutaneous and CNS pathology [98]

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