DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg Product Name Thalidomide-O-C6-amine HCl Synonyms

Product Name Thalidomide-O-C6-amine HCl Synonyms Thalidomide-4'-O-C6-amine HCl CAS Number 2245697-88-3 Related CAS 1957235-98-1 (free base) Molecular Formula C19H24ClN3O5 Molecular Weight 409

79 Purity (HPLC) >= 95% Solubility DMSO

This probe is also ef

AggFluor P1 exhibits fluorescence in both misfolded oligomers and insoluble aggregates but cannot differentiate between these species

Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody–drug conjugate (ADC) development

DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg Product Name Thalidomide-O-C6-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing