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Pre-filled pens, vials with syringes, and newer delivery formats each have nuances

There is no evidence that one timing is superior to the other pharmacologically, so choose what works for your schedule and tolerance

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the change in the number of nocturia episodes per 24 hours was -21.7 (p=0.001) and -1.51.8 (p=0.003) and the mean voided volume improved from 95 to 176 mL, and from 99 to 174 mL in those with and without nocturnal polyuria, respectively