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In the event ( that we later determine that the payment model that includes policies established under section 1899(i)(3) of the Act no longer meets this requirement, we would undertake additional notice and comment rulemaking to make adjustments to the payment model to assure continued compliance with the statutory requirements

The issue of adjusting for multiple testing within a study is widely debated

2018 Nov;27(6):656-662 Marynak K, Mahoney M, Williams KS, Tynan MA, Reimels E, King BA

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Angular cheilosis: The lateral lip fissures, well known among denture wearers, have been called by a variety of names, such as "rhagades", "perleche", "angular cheilitis", and "angular cheilosis"