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reported that the selective blockade of respiratory chain complex I by MPP + induces dopaminergic neuronal degeneration and PD symptoms, suggesting that defects in the respiratory chain play a role in the pathogenesis of PD [82]

In addition, homocysteine is recycled to methionine through BHMT

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These associations between miRNA expression profiles and diseases are often obtained by non-targeted screening (microarray or miRNome sequencing), and their mechanistic roles in physiology or pathophysiology are poorly studied

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Under these conditions, the essential trace element, selenium (Se), can confer various biological benefits to humans and animals, especially due to its anticancer, antiviral, and antioxidant properties, as well as its ability to regulate immune responses