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The effects of SLU-PP-332 and 5-amino-1MQ on mitochondrial function and cellular energy pathways

While topical application has minimal systemic absorption, the precautionary principle suggests avoiding use during pregnancy unless a healthcare provider approves

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This explains the different side effect profiles

5-Amino-1MQ is a first-in-class small molecule inhibitor designed to target Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that acts as a master regulator of the cellular "metabolic drain."

Blocking NNMT raises cellular NAD+, which in research supports fat-cell metabolism and fat loss