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In the brain, hyperglycaemia activates microglia, and microglia activation and polarisation can mediate central inflammatory responses, neuronal apoptosis and exacerbate central neuropathy leading to dementia (28)

NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism

Mechanism of action of sulforaphane: Inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response elementmediated heme oxygenase-1 in human hepatoma HepG2 cells