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We selectively reexpressed 2 nAChRs in VTA dopamine or VTA -amino-butyric acid (GABA) neurons in 2/ mice to double-dissociate the aversive and rewarding conditioned responses to nicotine in nondependent mice, revealing that 2 nAChRs on VTA dopamine neurons mediate nicotines conditioned aversive effects, while 2 nAChRs on VTA GABA neurons mediate the conditioned rewarding effects in place-conditioning paradigms

How conspiracy theorists explain Trump officials' pivots on Jeffrey Epstein How Trump officials are getting tripped up explaining Jeffrey Epstein's death The current leaders of the FBI are men who spent years building suspicions and entertaining conspiracy theories about the agency they now run

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