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Figure 3 illustrates the overall therapeutic mechanism of action of H

In enterocytes, hypoxia-inducible transcription factor (HIF-2), a mediator of cellular adaptation to hypoxia, has been shown to regulate iron absorption after changes in systemic iron levels via direct transcriptional activation of DMT1, DCYTB, and FPN (Shah et al., 2009[381]

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Vitamin D deficiency is a major risk factor for NAFLD pathogenesis