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Decreased NAD + levels can impair the efficiency of the mitochondrial respiratory chain, resulting in reduced energy production, which may exacerbate obesity and related metabolic disorders (Amjad et al., 2021)

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Cleavage reactions were conducted with 250 M substrate in 100 mM glycine pH 3.0 at 37 C, in the presence of 0.5 M Clc and/or 10 M pepsin

While a true sensitivity to the peptide molecule is possible, its exceedingly rare