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[PubMed] Yazulla S

This study also investigated microglia-specific TRPM2 deletion, as well as neuron-specific deletions using CaMKII-Cre (excitatory neurons) and parvalbumin-Cre (GABAergic interneurons)

Thus, a lower homocysteine level in a person with high free radical / reactive oxygen species tells me that their body is trying to fight it by producing glutathione