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Description

Mar 2015;110(2):4

11, e0252622

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In contrast, the dose used in our study (10 g/kg/day) likely results in supraphysiological concentrations during the treatment period, which may be necessary to achieve therapeutic effects in a disease state where endogenous irisin production or signaling could be impaired

Cryo-EM sample preparation and data collection To prepare the cryo-EM samples of wtVLP and sVLP, a 2.4 l aliquot of the sample was applied onto a plasma-cleaned lacey-carbon grid (Cu, 400 mesh, Ted Pella)