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Free radicals are unstable molecules generated by everyday exposure to pollution, UV radiation, processed foods, chronic stress, and normal metabolic processes

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Vitamin C deficiency not only affects the skin's antioxidant defenses but also impacts essential skin functions

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Furthermore, E2-BSA does not promote proliferation of NSPCs, but it does mimic the increase in the generation of oligodendrocytes, strongly suggesting that the oligodendroglial generation from NSPCs is likely to be stimulated via membrane-associated ERs (Okada et al., 2010)