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This therapy involves the isolation of platelets from the blood plasma to make them concentrated

Trendelenburg AU, Meyer A, Rohner D, Boyle J, Hatakeyama S, Glass DJ

In diabetes, diminished abundance of Akkermansia , Bacteroides , Bifidobacterium , Faecalibacterium , and Roseburia reduces -glucuronidase and 7-dehydroxylase activities, thereby blocking the conversion of primary BAs to secondary BAs and consequently decreasing the synthesis of DCA and LCA (Li et al., 2021b)

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For confirmed deficiency or pernicious anaemia, NICE Clinical Knowledge Summaries recommend hydroxocobalamin 1mg intramuscularly, with frequency determined by the underlying cause and neurological involvement