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This hypothesis is consistent with the two characteristics, genome instability and mutation and tumor-promoting inflammation, that enable the acquisition of the hallmarks of cancer defined by Hanahan and Weinberg [25]

Neuroanatomic changes and their association with cognitive decline in mild cognitive impairment: a meta-analysis

American Journal of Preventive Medicine, 2015

Some people in the Americas and the Caribbean may raise objections to the smell of cannabis when smoked or vaped near them despite the substance having a legalized status