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The paucity of relevant environmental data for certain hazardous pharmaceuticals must be addressed to help prioritize compounds that require further research ( In summary, SSRIs are associated with the potential risk of pharmaceutical contamination in aquatic environments that may impact the reproductive development of aquatic animals, with implications for the adaptation of populations in response to current and future environmental challenges

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Crucially, this cross-talk is a two-way street: CNS pathology or stress can alter gut function and microbiota, potentially creating a vicious cycle [13]

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