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After 6 weeks of continued patch usage, switch to the next step (step 2 or 3)

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Preliminary data indicate that MDM2-depleted cells expressing a missense mutant p53 (L194F) exhibit decreased phosphorylation of PARN in chromatin fractions, as identified by mass spectrometry

It's helpful to define certain words in your Acceptable Use Policy to minimize the risk of misinterpretation