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Research indicates that HIF-1-induced long non-coding RNA (lncRNA) PMAN can regulate ferroptosis by maintaining the mRNA stability of the ferroptosis-related gene SLC7A11, inhibiting ferroptosis and contributing to subchondral bone remodeling (Lin et al., 2022)

ABCR, Karlsruhe, Germany) were used as starting materials

The linear mixed-effects model (LMM) was constructed to account for both fixed and random effects, ensuring a robust analysis of the longitudinal data, so we applied LMM to analyze the longitudinal outcome variables including instrument scores (for patients 37 and 920) and LPP substrate amplitudes (for patients 1120), for which the model included fixed effects for relapse status and time (different time points [TPs], defined in Supplementary Methods 3.8 and 9.3) and a random effect of patient ID

Mitochondria-targeted antioxidants, a new class of antioxidant chemicals for neurodegenerative diseases: perspectives and limitations

Side effects too severe Reduce dose temporarily : Go back to previous dose for 2 more weeks

Anxiety is a feeling of worry, nervousness, or fear about an event or situation