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In contrast, MEL does not display redox cycling, thus, it does not stimulate oxidation

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Biomed Pharmacother 135:111225

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Endometriotic implants secrete estradiol (E2) as well as prostaglandin E2 (PGE2), agents that attract macrophages (monocyte chemotactic protein 1[MCP-1]), neurotrophic peptides (nerve growth factor [NGF]), enzymes for tissue remodeling (matrix metalloproteinases [MMPs]) and tissue inhibitors of MMPs (TIMPs), and proangiogenic substances such as vascular endothelial growth factor (VEGF) and interleukin-8 (6)

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Enhanced research on routes of administration could improve efficacy and reduce the likelihood of adverse effects (vi) Establishing reliable methods for the mass production of bacteria-nanomaterials hybrids is of great importance and key to reducing the cost and improving the accessibility of therapies

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