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In a phase III trial ( NCT03668496 (first posted: 12 September 2018) ), camrelizumab plus chemotherapy such as carboplatin and paclitaxel could dramatically extend the PFS (9.1 months) and median OS (18.2 months) in patients with advanced NSCLC (183)

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Wheels have to roll along an unbroken supporting ridge, but legs can be placed on a series of separate footholds, an extretne example being a ladder

The Devil wears Prada (2005) The movie adaptation of the eponymous novel