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VSIG4 ameliorates intestinal inflammation through inhibiting macrophages NLRP3 inflammasome and pyroptosis

Novo Nordisk is advancing CagriSema toward commercial launch while also developing amycretin, a single-molecule dual GLP-1/amylin agonist that could eventually replace the two-injection CagriSema protocol with a single compound

J Med Chem 64:216232 Alizadeh AM, Faghihi M, Khori V, Sohanaki H, Pourkhalili K, Mohammadghasemi F, Mohsenikia MJP (2012) Oxytocin protects cardiomyocytes from apoptosis induced by ischemiareperfusion in rat heart: role of mitochondrial ATP-dependent potassium channel and permeability transition pore

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