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Hazard ratio (HR) estimates were calculated using a Cox proportional hazards model with effect for treatment

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Statements Data availability statement The original contributions presented in the study are included in the article/ Supplementary Material , further inquiries can be directed to the corresponding author/s

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BRD4 ET sample (0.2 mM) was placed in the cell, whereas the micro-syringe was loaded with the ASXL1 peptide (2.0 mM) in the ITC buffer