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Along with the high expression of SLC7A11, glucose deprivation can increase the ROS level of breast cancer cells through the AMPK/ACC pathway, thereby promoting the death of breast cancer cells (52)

doi: 10.1017/S0029665118001192 92 KravchenkoVZakharchenkoT

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By contrast, post-radiation administration of arsenic trioxide as a maintenance therapy may induce further damage through ROS and potentially reduce the ability of the tumor cells to repair the radiation-induced damage [72, 73]

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In addition, oxidative burst induced by leukocytes is an effective mechanism for fighting against microbes during infection (Saran et al., 1999