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86% of patients attempted to quit smoking, and 29% actually quit

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Overall, aspartate limitation induced by rotenone treatment or aspartate starvation in engineered auxotrophs produces similar aspartate/proliferation dynamics with three salient features: (1) proliferation defects lag changes in aspartate levels, with either paradigm showing an initial ~1224 h time window in which aspartate levels significantly decrease while proliferation remains constant