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Concerning potential DDIs between NRT and anti-TB drugs, DrugBank.com reports that the metabolism of nicotine can be decreased when combined with INH or EMB and increased when co-administered with rifabutin

Supplementary Figure 16

In other words, and this is a remarkable statistic if you think about it, a third of all Chinese men now aged 29 or younger will die prematurely of smoking-related illnesses