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CSE is also regulated during inflammation, for example, during LPS stimulation of macrophages, which leads to increased association of SP1 with the CSE promoter

10.1016/j.giant.2020.100022 91 WangD.-K.ZhengH.-L.ZhouW.-S.DuanZ.-W.JiangS.-D.LiB.et al (2022)

Enhancing endogenous NO production should provide physiological and more sustained effects

70 Non-oxidized dopamine is a neurotransmitter that inhibits erastin-induced GPX4 degradation in cancer cells

The mechanisms include reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression supporting neuronal survival, angiogenesis improving blood flow, and modulation of dopamine and serotonin systems