Moreover, MSC-Exos contain miRNAs that stimulate the Nrf2 antioxidant pathway [211], maintain the stability and function of SLC7A11 [166], and mitigate iron overload via DMT1 modulation [152]
Kwon, I
Plant Soil 279, 4150
Additionally, Ca 2+ overload induces K + efflux through Gardos channels [187] and promotes activation of cytoskeleton-degrading calpain [188], which consequently leads to the cell shrinkage and membrane blebbing, respectively
In cosmetics, it is particularly interesting because it can help the skin counteract oxidative stress, one of the factors that contributes to dullness, discoloration, inflammation, skin aging, and an uneven complexion
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