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High ATP demand, in combination with dysfunctional mitochondria, make these neuron groups more sensitive to degeneration (Wang and Michaelis, 2010)

542 Although tau protein aggregation and beta-amyloid protein (A) accumulation play central roles in the pathophysiological hypothesis of AD, the potential role of metal overload, subsequent oxidative stress, and tissue damage cannot be ignored

FSP1 uses NAD(P)H, while the reduced form of ubiquinone captures lipid peroxyl radicals that cause LPO

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Compatible solutes contribute to heat resistance and ribosome stability in Escherichia coli AW1.7

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