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Ishizawa J, Zhao R, Heese L, Jaeger A, Nishida Y, Jacamo RO, Kojima K, John Ma MC, Ruvolo V, Chachad D, Devine W, Lindquist S, Davis R, Porco JA, Jr, Whitesell L, Andreeff AM

Deletion of circRNAs enhances autophagy, leading to apoptosis and reduced proliferation in cervical cancer cells

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The miRNA duplex is loaded into a silencing complex that contains an Argonaute protein, and eventually, the mature single-stranded miRNA is retained by the Argonaute to target substrate mRNAs (Matranga et al, 2005

One bacterium (Clostridium symbiosum) chops EGT into an electron acceptor called thiourocanic acid (TUA), and a second, unrelated bacterium (Bacteroides xylanisolvens) then breathes that TUA to roughly quadruple its own ATP output and grow faster under the oxygen-free conditions of the colon