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Pedicularis plicata Liao R et al., Phytotherapy Research 1999 13(7):621-623

Clinical evidence supports B12's role in energy metabolism and neurologic function

The bacteria are both horizontally and vertically transmitted and can be engineered to reduce the lifespan of the insect

Within the mitochondria, adenosylcobalamin serves as an absolute, non-negotiable requirement for the function of an enzyme called methylmalonyl-CoA mutase (MUT)

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To ensure the proper function of SLC7A11 in maintaining redox homeostasis, the expression and activity of SLC7A11 is strictly regulated by a variety of mechanisms, including transcriptional and epigenetic regulator-mediated transcriptional regulation, as well as post-transcriptional regulatory mechanisms