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Postmenopausal women who carried the MTHFR C677T variant were found to be at a 2 to 3-fold increased risk of depression.[ref] I do want to point out that not all studies agree, and some researchers find that the MTHFR C677T variant has little to no impact on depression risk

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474 Amino acid deprivation therapy utilizes enzymes secreted by microorganisms in anticancer treatments by exploiting the metabolic differences between cancerous and normal cells