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Alcohols boil considerably higher than comparably sized ethers (first two entries), and isomeric 1, 2 & 3-amines, respectively, show decreasing boiling points, with the two hydrogen bonding isomers being substantially higher boiling than the 3-amine (entries 5 to 7)

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Mol Med Rep 23(1):88

Supplementary Validation Method: LCMS/MS For high-sensitivity detection requirements, liquid chromatographytandem mass spectrometry is used for supplementary validation, especially suitable for trace component analysis and metabolic studies

Loss of Lean Muscle Mass: If muscle mass decreases, so does the resting metabolic rate (RMR) , making it harder to continue burning calories