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It was recently postulated that the gut microbiota may influence CIPN through macrophages [110], and after chemotherapy, the number of CD11b + CD45 hi cells, which are presumably macrophages, is significantly lower in the dorsal root ganglia of mice that receive water containing antibiotics than those receiving water alone [136]

doi: 10.1016/j.cmet.2022.07.013

Ratios between fat to protein plus carbohydrate range typically between 1:1 and 1.5:1, but can reach 4:1