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Between 0.10% to 0.20%, there can be decreased reaction times, slurred speech, confusion, and vomiting

The mean age of patients was 58 years, 4% were 75 years or older and 54% were male

Figure 6: Kaplan-Meier Curves for Overall Survival in Non-Squamous NSCLC in Study JMEN Figure 7: Kaplan-Meier Curves for Overall Survival in Squamous NSCLC in Study JMEN Maintenance Treatment Following First-line Pemetrexed Plus Platinum Chemotherapy The efficacy of pemetrexed as maintenance therapy following first-line platinum-based chemotherapy was also evaluated in PARAMOUNT (NCT00789373), a multi-center, randomized (2:1), double-blind, placebo-controlled study conducted in patients with Stage IIIb/IV non-squamous NSCLC who had completed four cycles of pemetrexed in combination with cisplatin and achieved a complete response (CR) or partial response (PR) or stable disease (SD)

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Individual results may vary based on wound characteristics and overall health