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A 2025 study in the journal Tobacco Control said vaping may be linked to adverse mental health outcomes and that those who quit experience fewer urges to vape, reduced anxiety, and stabilized mood. Teens decisions are often based on their peers and whats cool, said Anthony Alberg of the University of South Carolina, a member of the expert committee that produced the National Academies vaping report

In clinical trials for Epidiolex, many research participants reported relatively mild side effects, such as fatigue and digestive issues