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Therefore, metabolic phenotyping, through techniques like transcriptomics, metabolomics, or functional imaging (e.g., FDG-PET), could be a crucial strategy for identifying patients most likely to benefit from mitophagy-directed therapies

After single-cell dissociation of iPSCs with TrypLE Select Enzyme, cells were plated on Matrigel-coated 6-well tissue culture plates with ROCK inhibitor

It was initially suggested that unusually high activity of TPMT may shift the metabolic machinery toward thiopurine methylation

Chem Res Toxicol 19(7):894898

Chen J, Yuan M, Madison CA, Eitan S, Wang Y

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