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Also shown are the adverse clinical outcomes associated with elevated systemic TMAO levels in subjects, and enhanced cardiometabolic phenotypes observed with elevated TMAO levels in animal models (46, 12, 13, 1618)

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The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

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* Reference intake for an average adult (8400 kJ/2000 kcal)

The Ubiquitin-Proteasome System and Skeletal Muscle Wasting