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Accurate classification of childhood brain tumours by in vivo 1H MRS - A multi-centre study

A number of clinically and experimentally utilized chemotherapeutic drugs, including the cytostatic agent BCNU, gold and platinum complexes, and compounds acting at the dimer-interface have already been shown to inhibit TrxR1 effectively 2,3,7

It induces the MMP that triggers TrKP, then leads cells to release pro-BDNF and convert to BDNF