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We break exact linear dependency between the three explanatory variables (i.e., cohort = period age) and deal with under-identification by grouping birth cohorts into frequently used 5-year intervals, and, after confirmation of a curvilinear relationship, treat smoking as a quadratic function of age 30

SDS-PAGE sodium dodecyl sulfate polyacrylamide gel electrophoresis Guinea pig lung microsomes washed free of ascorbic acid, were prepared as described before (4)

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