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But what makes this especially harmful is how the tobacco industry has deliberately targeted women and girls for over a century

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The complications of frostbite include: Changes in the color of the skin Increased sensitivity to cold Issues with growth in children Infection Excessive sweating Prolonged numbness in the affected region Loss of nails or damaged nails Tetanus Hypothermia Amplified risk of being affected by frostbite again Stiff joints or frostbite arthritis Gangrene (death of body tissue due to lack of blood flow or infection

Results for all 5-star riskoutcome pairs are available in Table 2 and Supplementary Information 4.1

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As summarized here, a number of other tobacco smoke carcinogens also can cause G to T transversion mutations