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Generation of ROS is a common upstream mechanism implicated in NLRP3 inflammasome activation 20, 38

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Climbing stairs, walking quickly or taking part in physical activity can lead to shortness of breath much sooner than before

Perceptions of harmfulness of snus use and smoking on health Over half of the respondents or 58% (2600/4480) acknowledged that snus is harmful to health, but only 21% (956/4480) considered snus very harmful

The main reasons for the fall in smoking are the graphic warning on the cigarette packet cover, awareness programmes in schools, training programmes, capacity building and the enforcement teams present in every district and taluka, says Deputy director of the Medical, Health and Family Welfare Department Selvaraj

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