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Blocking GLN metabolism with the GLS inhibitor CB-839 results in GSH depletion [56, 57]

Although disulfidptosis has demonstrated broad prospects as a novel cell death mechanism in cancer research, current studies still face numerous challenges

Biochem Pharmacol 27:2859-2863 Muldrew KL, James LP, Coop L, McCullough SS, Hendrickson HP, Hinson JA, Mayeux PR (2002) Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection

Gastroenterology 2006

Another trial evaluated the effects of CoQ10 supplementation (150 mg daily) for 7 days preceding scheduled coronary artery bypass grafting (CABG) procedures in 40 subjects who were divided to receive CoQ10 or act as a control group